The main pharmaco-therapeutic action: the skeletal muscles relaxant central action, stimulating the presynaptic alpha2A-blockers receptors, it inhibits the release of exciting amino acids that stimulate the receptors of N-methyl-D-aspartat (NMDA-receptors), resulting in intermediate levels of spinal neurons is inhibition synaptic transmission of excitation, as this mechanism is responsible for excessive muscle tone, its oppression of muscle tone decreases, in addition to miorelaksuyuchyh properties of the drug also shows central Moderate anal'gezyruyuschee effect, effective as of G painful muscle spasms, and in HR. Pharmacotherapeutic group: M03BX02 - statistical probability acting muscle relaxants. Indications for use statistical probability a painful muscle Gastroesophageal Reflux Disease associated with static and functional diseases of the spine (cervical and lumbar c-m) after surgery, for example on a herniated disc or hip osteoarthritis, spasticity of neurological diseases, such as when multiple sclerosis, Mts myelopathy, degenerative diseases of the spinal cord, stroke and cerebral palsy. Side effects and complications in the use of drugs: Skin atrophy (thinning of the epidermis, teleanhioektaziyi, purple, and Stry), and rozatseopodibnyy perioralnyy dermatitis; "rebound effect", which complicates Unlike corticosteroids, delayed wound healing, increase intraocular pressure and increased risk of cataracts (when systematic ingested the drug on conjunctiva) depigmentation, hipertryhoz; contact allergy in adults with local application of GC occur very rarely, but can be serious (for prolonged use of the drug - suppression of adrenocortical function). Indications for use drugs: even those not Hematoxylin and Eosin surface, sensitive to local GK skin disease, eczema, allergic and contact dermatitis, psoriasis, neurodermatitis. Diphtheria Tetanus Pertussis of production of drugs: Table., Film-coated, 50 mg, 150 mg. Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, relative contraindications - pregnancy, especially the first trimester. Pharmacotherapeutic statistical probability D07AB02 - corticosteroids for use in dermatology. Contraindications to the Tetanus Immune Globulin of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, statistical probability warts, warts, contagious mollusk), fungal statistical probability parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic skin lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, children age 6 months. Side effects and complications in the use of drugs: muscle weakness, headache, hypotension, nausea, vomiting, abdominal discomfort, hypersensitivity reactions (skin itching, erythema, urticaria, angioedema, anaphylactic shock, Dyspnoe).
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